The Activity, Cognition and Emotion (ACE) Model of Symptoms
The ACE model was developed as a novel approach to the conceptualisation of mood disorders such as bipolar disorder and depression. Rather than conceptualising these disorders along a single dimension of mood, the ACE model considers mood disorders as a combination of symptoms across three domains: Activity, Cognition, and Emotion; that vary over time. This multidimensional and longitudinal perspective is consistent with the prevalence of complex clinical presentations, such as mixed states, and allows for more detailed formulation and management of mood disorders.
Irritability in Mood Disorders
This comprehensive review compiles the latest evidence regarding the conceptualisation of irritability within mood disorders, including how best to define and measure irritability, evidence from neuroimaging studies and potential treatments.